In January 2022
β-NMN was registered with the Chinese National Medical Products Administration as a cosmetic raw material and entered into a monitoring period.
Hangzhou Jumei New Material Technology Co. Ltd. was established, with an annual production capacity of hundreds of tons and a 30% reduction in the terminal price of β-NMN.
Human cells can be reprogrammed, and aging organs can be rejuvenated. In a two-year mouse experiment, it was proven that long-term use of NMN can extend the lifespan of mice by 30%.
Jeffrey C. Hall and two other research groups discovered that supplementing NAD+ precursor NMN can regulate disrupted biological clocks to restore normal daily rhythms.
Harvard Medical School Professor David Sinclair first discovered that NAD+ precursor NMN can significantly reverse aging and extend lifespans in dry mammals. Supplementing NAD+ in mice can prolong lifespan through mitochondrial pathways and DNA repair mechanisms.
It was discovered that NAD+ can extend the lifespan of various species: Leonard Guarente, Wood JG, and Bitterman KJ found that NAD+ can extend the lifespan of nematodes, fruit flies, and male mice to varying degrees.
Jack Preiss and Philip Handler first discovered that NAD+ played a key role as a coenzyme in energy metabolism and biological reactions.
NAD+ was first discovered and named by Sir Arthur Harden, and in 1929, it was awarded the Nobel Prize.