NAD+ levels and its preventive and therapeutic effects on seven age-related fields

Update:2023-06-28   

  Can increasing NAD+ levels help prevent and treat COVID-19? "NMN Guru" Sinclair supports this viewpoint with substantial evidence.

  In 2020, with the media's coverage, many people have learned about the NMN ingredient that has sparked an anti-aging craze in China. In the field of scientific research, new studies on NMN have constantly emerged, demonstrating its effectiveness in anti-aging and its preventive and therapeutic effects on various age-related conditions. This has prompted experts to call for the inclusion of this ingredient in standard treatment plans. Enjoy the following information!

1, Sinclair discovers new benefits of NMN! Protects the optic nerve and reduces retinal damage

Recently, Professor David Sinclair, known as the "Father of NMN" from Harvard University, published a paper in the top scientific journal "Aging" claiming that NMN has a strong protective effect on the optic nerve and significantly inhibits the further deterioration of retinal detachment and other related conditions.

Of particular interest is the fact that scientists had previously believed that the neuroprotective effects of NMN were derived from restoring declining NAD+ levels to a healthy state, emphasizing the principle of "making up for deficiencies."

However, Sinclair's research revealed that in specific situations, additional supplementation of NMN can actually be beneficial and further reduce retinal damage.

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Read the full article here:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7803565/


2, Breaking News! NMN can actually treat hair loss!

At the 71st Korean Dermatology Conference held recently, Professor Hang Cheol Shin from Chongshil University and his team unveiled their groundbreaking new hair regrowth technology.

Using microneedles, they implanted NMN along with a cocktail of growth factors called Cellcurin™ into the scalps of 20 patients suffering from androgenetic alopecia, also known as male pattern baldness.

After three months of treatment, all the patients showed significant improvement in hair volume and quality. Professor Hang Cheol Shin mentioned that they will now proceed with more advanced and large-scale clinical trials.

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Read the full article here:   http://www.papersearch.net/thesis/article.asp?key=3845080

 

3, International Authority: Supplementation of NAD+ Can Slow Muscle Aging and Greatly Extend Healthspan

On January 19, 2021, Professor Johan Auwerx, an absolute authority in mitochondrial research, published an article stating that supplementation of NAD+ can enhance mitochondrial function in various animal models, reduce amyloidosis, and significantly delay muscle aging, thus extending healthspan.

This research was published in the top scientific journal, "Cell," in a subjournal.

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Muscle aging is one of the main causes of a sudden decline in quality of life and overall health in middle-aged and elderly individuals. Professor Johan Auwerx's study not only identifies the causes of muscle aging but also emphasizes the effectiveness of NAD+ in slowing down and even reversing the aging process at the cellular level.

Read the full article here: :https://www.sciencedirect.com/science/article/pii/S2211124720316491#!

 

4, Cardiovascular Expert in China: Supplementing NAD+ is the Best Way to Prevent Cardiovascular Diseases 

Dr. Liu Qiming, Director of the Department of Cardiovascular Medicine at the Xiangya Second Hospital of Central South University, recently led a team to publish a comprehensive review article in the prestigious international journal "Clinica Chimica Acta," which thoroughly explores the important role of NAD+ in cardiovascular diseases.

In the article, Dr. Liu Qiming explicitly emphasizes that supplementing and stabilizing the levels of NAD+ in the body is currently one of the best ways to treat and even prevent cardiovascular diseases.

 

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Read the full article here: [Link: https://www.sciencedirect.com/science/article/abs/pii/S0009898121000218#!]


5, Italian Expert: NAD+ Supplements Can Effectively Repair Kidney Damage and Should be Included in Mainstream Treatment Plans

On January 26, 2021, several medical experts from Italy published a review in the international research journal "Antioxidants & Redox Signaling," stating that a large amount of experimental data in recent years indicates that NAD+ supplements have excellent repair effects on kidney damage. They call for the inclusion of NAD+ supplements in standard treatment plans for kidney damage.

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 The corresponding author of the article, Professor John Kellum, an expert in critical care medicine, stated that one of the indicators of kidney damage is abnormal mitochondrial function and a sudden decrease in NAD+ levels.

Boosting NAD+ levels through external supplementation is an ideal method for kidney function repair, both in terms of scientific principles and experimental data.

Read the full article here: [Link: https://www.liebertpub.com/doi/pdf/10.1089/ars.2020.8066]


6, New Evidence Shows NMN Protects Women's Reproductive Health by Safeguarding Oocytes from External Contaminants

On February 2, 2021, Professor Xiong Bo, one of the leading figures in NMN research in China from Nanjing Agricultural University, once again published an article in a renowned international journal, stating that NMN supplementation and mitochondrial repair capabilities can protect oocytes from various environmental toxins, significantly delaying female reproductive aging.

Professor Xiong Bo's research team found that many chemical additives in daily life, such as EGBE, can generate a large amount of reactive oxygen species (ROS), severely affecting mitochondrial function, and thus significantly reducing the quality of female oocytes, accelerating reproductive aging, and leading to infertility. However, NMN can effectively and precisely repair and prevent these problems. 

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Read the full article here: [Link: https://www.frontiersin.org/articles/10.3389/fcell.2021.628580/full]


7, Japanese Scientists Discover a New Mechanism of NMN's Anti-Aging Effects by Simultaneously Repairing Two Aging Markers

On February 2, 2021, Professor Takeshi Uchiumi, a renowned scholar from Kyushu University in Japan, announced their latest research findings that NMN can improve mitochondrial function, promote autophagy, enhance lysosomal function, and thereby enhance the protein homeostasis of the entire body. This mechanism simultaneously improves two aging markers, mitochondrial dysfunction, and protein homeostasis imbalance.

Since the proposal of the classic 9 aging markers, the majority of anti-aging research has focused on slowing down or even reversing specific aging markers. However, more and more evidence is indicating that NMN can simultaneously improve all nine aging markers, which is a promising prospect.

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 Read the full article here: [Link: https://www.embopress.org/doi/full/10.15252/embj.2020105268]